[HTML][HTML] The great migration and African-American genomic diversity

S Baharian, M Barakatt, CR Gignoux… - PLoS …, 2016 - journals.plos.org
… % in Europe, and 1.2% in the Americas, with increased African … out individuals contributing
more than 5% Native American … % Europeans among male contributors, but only 5.2% among …

[HTML][HTML] A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

RA Mathias, MA Taub, CR Gignoux, W Fu… - Nature …, 2016 - nature.com
genomes of 642 individuals from North and South American, … Moreover, leveraging our
high-coverage whole-genome data we … contributions across the genome. For example, in each …

Investigating mitonuclear interactions in human admixed populations

AA Zaidi, KD Makova - Nature ecology & evolution, 2019 - nature.com
… admixed individuals by the 1000 Genomes Admixture Group … enrichment in European
ancestry at high-mt genes in … a high level of concordance between the female contribution

[HTML][HTML] Replication of European hypertension associations in a case-control study of 9,534 African Americans

H Kaur, DC Crawford, J Liang, P Benchek… - Plos one, 2021 - journals.plos.org
… identified in European-descent individuals have equivalent … the African (AFR) samples from
the 1,000 Genomes Project, … associated with increased risk of hypertension in women (OR = …

[HTML][HTML] … of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics …

MCY Ng, M Graff, Y Lu, AE Justice, P Mudgal… - PLoS …, 2017 - journals.plos.org
… , and an additional seven loci by analyzing men and women … -analyses of both African and
European ancestry individuals, we … are needed to evaluate the contribution of rare variants in …

[PDF][PDF] Genetic consequences of the transatlantic slave trade in the Americas

SJ Micheletti, K Bryc, SGA Esselmann… - The American Journal of …, 2020 - cell.com
… platforms and Human Genome Diversity Panel individuals (HGDP)… A high proportion of
individuals from the Guianas (64%) and … European male and African female genetic contributions

[HTML][HTML] Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability

LE Duncan, A Ratanatharathorn, AE Aiello… - Molecular …, 2018 - nature.com
… broader goal of increased ancestral diversity in genomic data … Contributing studies provided
individual-level genotype data … sets with individual-level genotype data (versus SNP-level P-…

[PDF][PDF] Human demographic history impacts genetic risk prediction across diverse populations

AR Martin, CR Gignoux, RK Walters, GL Wojcik… - The American Journal of …, 2017 - cell.com
… -European proportion of GWAS participants has increased to … individuals, and the proportion
of individuals with African and … genome versus at GWAS catalog sites and identify elevated

[HTML][HTML] Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank

…, A Moscati, JE Rodriguez, CBIPM Genomics Team… - Genome Medicine, 2020 - Springer
… variants in non-European populations, and suggest that genomic screening in diverse patient
… The high proportion of AJ individuals in our cohort (14.0%) contributed to the high overall …

Health disparities and triple-negative breast cancer in African American women: a review

LA Newman, LM Kaljee - JAMA surgery, 2017 - jamanetwork.com
genes or in other genes associated with BC pathways might contribute to the increased risk
of TNBC in the African … in 3629 BC cases in African American individuals (approximately one-…